July 15, 2010 | Injection Treatments
8 minute read
Several new non-surgical options for wrinkle treatment and volume restoration may be introduced to the U.S. marketplace within the next year, as injectable fillers and wrinkle relaxers already being used in Europe undergo clinical trials and seek FDA approval.
The introduction of new cosmetic injectables not only offers patients more choices in facial rejuvenation, but also more competitive pricing and better results produced by better technology.
New hyaluronic acid fillers
Many of the new injectable fillers headed for the U.S. are composed of hyaluronic acid gel, including:
- Belotero (Merz), a hyaluronic acid (HA) filler similar to Juvederm offered in three concentrations—soft, basic and intense
- Restylane Vital & SubQ (Medicis), thinner and thicker formulations in the Restylane family of injectable HA fillers
- Juvederm Voluma & Hydrate (Allergan), thinner and thicker formulations in the Juvederm family of injectable HA fillers
Belotero has already been filed with the FDA and is purported to provide an improved level of tissue integration that causes fewer incidences of lumps and bumps than other hyaluronic acid fillers.
Juvederm Voluma is used throughout Europe for adding large amounts of volume to the face, such as the chin and cheeks. SubQ is also a large volume filler reportedly used for both facial contouring and body contouring, including buttock and breast augmentation.
Restylane Vital and Juvederm Hydrate are ideal for treating areas that have been historically difficult to correct with fillers, such as the back of the hands, décolleté and neck, and both purportedly offer wrinkle prevention by boosting skin hydration and elasticity.
Unlike Juvederm Hydrate, Restylane Vital offers a specialized automatic injection pen that regulates product injection volume and speed for more precise results.
Other innovative facial fillers
Novabel is the first injectable filler composed of spherical, flexible structures called Geleons, which are formed from marine brown algae extract. This patented Geleon technology reportedly makes Novabel injections virtually pain-free and also improves skin elasticity.
In addition, the composition of Novabel is said to make injection easier and reduce swelling, making it ideal for adding volume to facial areas with thin skin, such as the eyelids and tear troughs.
In addition to Novabel, another new non-HA filler is working its way to the U.S. Derma Veil, a pure collagen stimulator made of polylactic and polyglycolic acids (PLGA) will compete with Sculptra for a portion of the facial volume restoration market if approved.
Better than Botox? Naked botulinum type A injectables
In addition to injectable fillers, new botulinum type A neurotoxins Xeomin and PurTox are also poised to enter the U.S. marketplace.
Unlike Botox and Dysport, the active protein structures of PurTox and Xeomin products are not complexed to other, inactive proteins, leaving the active proteins “naked.”
As a result, it is theorized that these wrinkle relaxers may work faster, last longer and decrease the possibility of allergic reaction and development of blocking antibodies in patients.
PurTox has completed clinical trials and may be close to FDA approval.
A New Era of Injectable Innovation Is Coming
Facial rejuvenation is on the brink of a major evolution as the U.S. prepares to welcome a host of next-generation injectables that are already popular across Europe. These include advanced hyaluronic acid fillers and “naked” botulinum type A wrinkle relaxers, all designed to provide better, longer-lasting results with minimal risk and downtime. As these products approach FDA approval, patients in Eugene and beyond—especially those under the care of renowned plastic surgeon Dr. Lee B. Daniel—can anticipate a broader range of options for restoring youthful contours and smoothing dynamic lines.
Hyaluronic Acid Fillers: Smarter Formulations for Natural Results
Among the most exciting developments are new formulations of hyaluronic acid (HA) fillers. These products are created to address both fine lines and deeper volume loss while minimizing common issues such as swelling and lumps.
Belotero: Seamless Integration with Skin Tissue
Belotero, produced by Merz, is already making waves in Europe for its unique tissue integration. Unlike older fillers that may leave visible ridges or bumps, Belotero blends more evenly into the skin, making it an ideal choice for delicate areas like under the eyes or around the lips. With three levels of density—soft, basic, and intense—providers like Dr. Daniel will be able to customize treatments more precisely for each patient’s needs once FDA approval is secured.
Restylane Vital & SubQ: Versatility from Hands to Cheeks
Restylane has long been a leader in HA fillers, and their new formulations promise even more versatility. Restylane Vital is a thinner product perfect for treating areas such as the neck, décolleté, and hands—places where fine skin requires gentle hydration and elasticity. The thicker SubQ version, on the other hand, is ideal for facial contouring and even body contouring applications like non-surgical buttock enhancement. Patients at Aesthetic Plastic Surgery in Eugene may soon benefit from these expanded applications as the products progress toward U.S. availability.
Juvederm Voluma & Hydrate: Facial Volume and Deep Moisture
Juvederm Voluma, another HA filler in the Allergan family, has already gained popularity overseas for restoring volume in larger facial areas such as the cheeks and jawline. When sagging or hollow areas age your appearance, Voluma’s dense formulation can provide natural-looking lift and contour. Juvederm Hydrate, on the other hand, targets hydration deep within the skin—perfect for those wanting to refresh areas where topical treatments fall short.
At Dr. Daniel’s practice, these fillers could offer exciting enhancements to existing treatment plans, delivering more individualized and longer-lasting rejuvenation.
The Rise of Specialized Fillers
Novabel: The Future of Painless Injection
One of the more groundbreaking new entries is Novabel, which uses a patented “Geleon” technology—flexible, spherical structures derived from marine brown algae. Novabel not only boosts elasticity but also promises virtually pain-free injection. Its unique structure also reduces the likelihood of swelling, making it ideal for sensitive areas like under the eyes or near the tear troughs.
Dr. Lee Daniel’s emphasis on comfort and natural results makes Novabel an exciting prospect for future non-surgical treatment offerings at his Eugene practice.
Derma Veil: Collagen Stimulation Without HA
Another noteworthy contender is Derma Veil, a collagen stimulator composed of polylactic and polyglycolic acids (PLGA). Unlike HA fillers that add volume directly, Derma Veil stimulates the body to produce its own collagen over time. This makes it a viable alternative to Sculptra, and an excellent option for patients looking for gradual, natural-looking enhancement. Pending FDA approval, this filler could soon complement Dr. Daniel’s current range of services, especially for patients with more severe facial volume loss.
Beyond Fillers: Next-Gen Wrinkle Relaxers
Not all facial rejuvenation is about volume—sometimes, smoothing out expression lines is the top priority. While Botox and Dysport have long been the gold standards for muscle-relaxing treatments, two new neurotoxins, Xeomin and PurTox, may soon enter the U.S. market with promising differences.
Xeomin and PurTox: The “Naked” Neurotoxins
Unlike Botox and Dysport, which contain accessory proteins, Xeomin and PurTox are composed solely of purified botulinum toxin type A. These “naked” versions are believed to:
- Act more quickly
- Last longer
- Minimize allergic reactions
- Reduce the risk of developing resistance over time
PurTox has already completed clinical trials and is nearing FDA approval. With less risk of developing antibodies, these wrinkle relaxers could revolutionize maintenance treatments for patients requiring long-term care.
Dr. Daniel’s highly trained injectors at Aesthetic Plastic Surgery already offer leading neuromodulators. Once Xeomin and PurTox are FDA-cleared, patients will have the opportunity to choose the product that aligns best with their needs and long-term goals.
Competitive Pricing and Custom Treatment Plans
One of the biggest advantages of these upcoming injectables is the increased competition in the U.S. aesthetic market. With more brands available, pricing structures may become more patient-friendly. This enables practices like Dr. Lee B. Daniel’s to offer more value without compromising quality, safety, or results.
In addition, having a wider array of tools allows providers to tailor treatment plans more specifically. For example, a patient could benefit from Juvederm Voluma to restore cheek volume, Restylane Vital to improve hand texture, and Xeomin to relax forehead wrinkles—all in a single coordinated rejuvenation plan.
Why Choose Dr. Lee B. Daniel for Injectable Rejuvenation
With over three decades of experience and dual board certification, Dr. Lee B. Daniel is one of Oregon’s most trusted names in aesthetic medicine. His Eugene-based clinic, Aesthetic Plastic Surgery, combines cutting-edge medical technology with compassionate, individualized care. Patients who trust their rejuvenation to Dr. Daniel receive expert guidance in selecting the safest, most effective non-surgical treatments.
As these next-generation injectables receive FDA approval and become available in the U.S., Dr. Daniel will be among the first to offer them to eligible patients—ensuring results that are both scientifically backed and artistically refined.
Stay Ahead of the Aesthetic Curve
The coming year promises to bring a wealth of new, exciting options for facial rejuvenation. From hyaluronic acid-based volume enhancers like Belotero and Juvederm Voluma to purified neurotoxins like Xeomin and PurTox, the industry is poised for transformation. These innovations give patients more tools than ever to achieve their aesthetic goals with less downtime and greater customization.
To learn more about current injectable options or to be among the first notified when new treatments become available, schedule your consultation with Dr. Lee B. Daniel today. The future of wrinkle reduction and volume restoration is bright—and it’s closer than you think.